Drug Name

Serophene (Clomiphene)

Drug Uses

Serophene is used for treating female infertility and for certain conditions as determined by your doctor.

How to use

Use Serophene as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Serophene by mouth with or without food.
• Properly timed sexual intercourse is important for good results. Ovulation usually occurs 5 to 10 days after a dose of Serophene.

Drug Class and Mechanism

Serophene is an ovulatory stimulant. It works by helping to produce more hormones that cause your ovaries to release 1 or more eggs.

Missed Dose

If you miss a dose of Serophene, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store Serophene at 77 degrees F (25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Serophene out of the reach of children and away from pets.

Warnings/Precautions

Do not use Serophene if:

• you are allergic to any ingredient in Serophene;
• you are pregnant;
• you have abnormal vaginal bleeding;
• you have ovarian cysts (small growths on the ovaries) or enlargement not due to polycystic ovarian syndrome;
• you have or have ever had blockage of blood vessels (blood clots) in the legs, lungs, or other parts of the body;
• you have liver problems, uncontrolled thyroid or adrenal gland problems, or a brain lesion (e.g., pituitary gland tumor) .

• Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Enlargement of the ovaries may happen during or shortly after taking Serophene . Call your health care provider if you experience any stomach or pelvic pain, weight gain, pain, or stomach enlargement or discomfort while taking Serophene.
• Pregnancy with more than 1 fetus (e.g., twins) is possible while you are taking Serophene . Be sure you have discussed the potential complications and hazards of multiple pregnancy;
• Lab tests, including pregnancy tests, may be performed while you use Serophene . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Serophene with caution in the elderly; they may be more sensitive to its effects.
• Pregnancy and breast-feeding: do not use Serophene if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Serophene is found in breast milk. Do not breast-feed while taking Serophene.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

• blurred vision or vision problems (spots or flashes); breast tenderness; dizziness; enlarged breasts; enlargement of the ovaries; flushing; headache; hot flashes; lightheadedness; mood change; nausea; pelvic pain or bloating; stomach pain; vomiting.

• severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)increased risk of cancer of the ovaries; over stimulation of the ovaries; spontaneous abortion.

More Information

Serophene is to be used only by the patient for whom it is prescribed. Do not share it with other people.